Investigation revealed that conolidine and cannabidiol drastically blocked Cav2.2 channels. Within the peripheral and central nervous process, Cav2.two channels are located predominantly at presynaptic terminals32 and Participate in essential roles in suffering perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds that influence presynaptic Cav2.tw... https://englandy268swv2.mycoolwiki.com/user