Complicating drug interactions more, lumacaftor is alone a powerful inducer of CYP3A and will thus Restrict the efficacy of medicines that are cleared by way of this metabolic pathway. In particular, the efficacy of hormonal contraceptives is impaired and different ways of contraception needs to be applied to prevent pregnancy https://fernandogkosu.techionblog.com/28554612/details-fiction-and-e7449