Injectable codeine is readily available for subcutaneous or intramuscular injection only; intravenous injection is contraindicated, as this may lead to nonimmune mast-mobile degranulation and ensuing anaphylactoid response. Codeine suppositories may also be marketed in a few nations. In Ireland, new restrictions arrived into effect on one August 2010[ninety] concerning codeine, https://www.codeingil.com/