Epidural clonidine employed being an adjunct to local anesthetics has 3 different mechanisms of action. 1st, the stimulation of alpha-2-receptors in the dorsal horn lessens suffering transmission. Secondly, clonidine could cause nearby vasoconstriction that limits vascular elimination of local epidural anesthetics. Clonidine treats substantial hypertension by stimulating α2 receptors https://margaretr813jkh4.howeweb.com/profile