These final results, together with a prior report demonstrating that a small-molecule ACKR3 agonist CCX771 exhibits anxiolytic-like behavior in mice,two assist the notion of concentrating on ACKR3 as a unique strategy to modulate the opioid system, which could open up new therapeutic avenues for opioid-associated Diseases. Publishing this critique https://tupenie580uwt1.wikissl.com/user