Pentobarbital will decrease the level or effect of vinblastine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of exemestane by affecting hepatic/intestinal enz... https://socialwebnotes.com/story5425543/considerazioni-da-sapere-su-pentobarbital-half-life